Sean Myles

Research interests

Our research group focuses on using genetic data to detect and dissect the effects of domestication and breeding on various crops, especially grapes and apples. By sequencing and analyzing our food's DNA, we are unraveling the story of our intimate relationship with the organisms that sustain us. The insights we gain not only give us a better understanding of our past, but they also inform us on how to better manage our food supply in the future. To find out more about our lab, visit www.cultivatingdiversity.org.

Selected publications

• McClure, K.A., Sawler, J., Gardner, K.M., Money, D., Myles, S. (2014) Genomics: a potential panacea for the perennial problem.  American Journal of botany 101:1597 [PubMed:25326620]
• Garnder, K.M., Brown, P.J., Cooke, T.F., Cann, S., Costa, F. Bustamante, C.D., Velasco, R., Troggio, M., Myles, S. (2014) Fast and cost-effective genetic mapping in applie using next-generation sequencing. Genes, Genomes, Genetics 4:1681 [PubMed:25031181]
• Myles S (2013) Improving fruit and wine: what does genomics have to offer? Trends in Genetics 29:190 [PubMed:23428114]
• Sawler J, Reisch BI, Aradhya MK, Prins BH, Zhong GY, Schwaninger H, Simon C, Buckler ES, Myles S (2013) Genomics assisted ancestry deconvolution in grape. PLoS ONE 8:e80791 [PubMed:24244717]
• Kenny E, Timpson N, Sikora M, Yee MC, Moreno-Estrada A, Eng C, Huntsman S, Gonzalez Buchard E, Stoneking M, Bustamante CD, Myles S (2012) Melanesian blond hair is caused by amino acid change in TYRP1. Science 336:554 [PubMed:22556244]
• Myles S, Boyko AR, Brown PJ, Grassi F, Owens CL, Aradhya M, Prins B, Reynolds A, Chia JM, Ware D, Bustamante CD, Buckler ES (2011) Genetic structure and domestication history of the grape. PNAS 108:3530 [PubMed: 21245334]
• Myles S, Chia J-M, Hurwitz B, Simon C, Zhong GY, Buckler E, Ware D (2010) Rapid Genomic Characterization of the Genus Vitis. PLoS ONE5:e8219 [PubMed: 20084295]