Dr. Fraser Clark

Education

B.Sc. Biochemistry and Molecular Biology (Dalhousie University)
M.Sc. Pathology and Molecular Medicine (Queen’s University)
Ph.D. Pathology and Microbiology (University of Prince Edward Island)
Postdoctoral Fellow (AVC Lobster Science Centre)

Teaching

BVSC 3000: Veterinary Immunology
BVSC 3001: Veterinary Epidemiology

I am a molecular immunologist working on a variety of animal species to examine the amazing diversity and pathogen targeting ability of innate immune molecules. My lab uses high-throughput sequencing and other molecular techniques to answer comparative immunological and physiological questions in a variety of species including crustaceans and molluscs. In addition, we are examining the host-pathogen-environment interactions between a variety of marine pathogens, pollutants and their hosts.

Research Webpage: www.crustaceanhealth.ca

ResearchGate: www.researchgate.net/profile/K_Fraser_Clark

Selected Publications

L. Taylor, N. Mann, D. Daoud, K. F. Clark, M. R. van den Heuvel, S. J. Greenwood (2018) Effects of sublethal chlorpyrifos exposure on postlarval American lobster (Homarus americanus). Submitted to Ecotoxicology and Environmental Safety May 22, 2018.

L-M. D. Roux, S. J. Greenwood, P. J. Byrne, M. Fast, K. F. Clark. (2017). Impact of water temperature on immune-related gene expression in Homarus americanus experimentally infected with White Spot Syndrome Virus. Submitted to Journal of Invertebrate Pathology on November 15, 2017.

L-M. D. Roux, P. J. Byrne, S. J. Greenwood, K. F. Clark, G. M. Wright, D. W. Wadowska. (2017) Histological and ultrastructural assessment of American lobster (Homarus americanus) experimentally infected with White Spot Syndrome Virus. Submitted to Journal of Invertebrate Pathology on September 14, 2017.

J. Bojko, A. M. Dunn, P. D. Stebbing, K. S. Bateman, K. F. Clark, R. C. Kerr, S. E. Stewart-Clark, A. Johannesen, G. F. Stentiford. (2018) Symbiont profiles of green crabs (Carcinus maenas) along a North Atlantic invasion route, Diseases of Aquatic Organisms, Accepted in February 2018.

C. E. Davies, A. F. Johnson, E. C. Wootton, S. J. Greenwood, K. F. Clark, C. L. Vogan, A. F. Rowley. (2017) Disease ecology of a brown crab (Cancer pagurus) population in a temperate marine protected area. Submitted to ICES Journal of Marine Sciences.

K. F. Clark, J. Yang, A. R. Acorn, J. J. Garland, S. E. Stewart-Clark, S. J. Greenwood. (2017) The impact of harvesting location on American lobster (Homarus americanus) during live storage. Journal of Crustacean Biology. 37 303-314

L. Benestan, J-S. Moore, B. J. G. Sutherland, J. L. Luyer, H. Maaroufi, C. Rougeux, E. Normandeau, N. Rycroft, J. Atema, L. N. Harris, R. F. Tallman, S. J. Greenwood, K. F. Clark, L. Bernatchez. (2017) Sex matters in massive parallel sequencing: Evidence for biases in genetic parameter estimation and investigation of sex determination systems. Accepted by Molecular Ecology.

J. Bojko, K. F. Clark, D. Bass, A. M. Dunn, S. E. Stewart-Clark, P. D. Stebbing, G. D. Stentiford. (2016) Parahepatospora carcini n. gen., n. sp., a parasite of invasive Carcinus maenas with intermediate features of sporogony between the Enterocytozoon clade and other Microsporidia. Journal of Invertebrate Pathology. 143 124-134.

L. Benestan, B. K. Quinn, H. Maaroufi, M. Laporte, K. F. Clark, S. J. Greenwood. R. Rochette, L. Bernatachez. (2016) Seascape genomics provides evidence for thermal adaption and current-mediated poplation structure in American lobster (Homarus americanus). Molecular Ecology 25 5073-5092.

K. F. Clark, S. J. Greenwood (2016) Next-generation sequencing and the crustacean immune system: the need for alternatives in immune gene annotation. Integrative and Comparative Biology 56 1113-1130.

K. F. Clark, D. Wadowska, S. J. Greenwood. (2016) Aerococcus viridans var. homari: the presence of capsule and the relationship to virulence in American lobster (Homarus americanus). Journal of Invertebrate Pathology 133 20-26.

K. F. Clark, A. R. Acorn, H. Wang, S. J. Greenwood. (2015) Comparative tissue expression of American lobster (Homarus americanus) immune genes during bacterial and scuticociliate challenge. Fish and Shellfish Immunology 47 1054-1066.